Diseases of the cardiovascular system should be understood as any pathological functions of the heart or blood vessels arising as a result of numerous factors. It is known that heart disease is one of the main threats to the modern health care system, which causes global damage to public health. WHO reports that cardiovascular disease is the leading cause of death, and almost one in three deaths worldwide is due to heart disease (WHO, 2021). Preventive measures and healthy lifestyles are known to reduce the risk of cardiovascular dysfunction significantly. The evidence shows that up to 80% of diseases can be prevented with the use of appropriate preventive measures (AHA, 2018). Thus, one of the critical challenges for today’s health care system is becoming the development of preventive control measures for the development of cardiovascular pathologies.
The pathogenesis of a disease is multiple in nature and can be either infectious or non-infectious. It is indicated that the cause of the pathology depends on the further development of the disease and the complexity of its course (Du et al., 2018). In the case of non-infectious factors, genetic or epigenetic mutations that lead to the impairment of the functional activity of cardiac systems may be the causes for the development of the disease. In this context, single-nucleotide polymorphisms can cause damage to the genes responsible for normal cardiac system function, which causes dysfunction. As a consequence, the patient is more likely to develop life-incompatible outcomes, including heart attacks, complicated heart failure, and strokes. Even when sudden death does not occur, individuals’ quality of life is significantly reduced by having to take medications and see a cardiologist regularly and monitor biological metrics, including blood pressure and heart rate. The present study aims to examine the causes of heart disease in terms of impaired epigenetic constructs.
References
AHA. (2018). CDC prevention programs. American Heart Association. Web.
Du, Y., Zhang, G., & Liu, Z. (2018). Human cytomegalovirus infection and coronary heart disease: A systematic review. Virology Journal, 15(1), 1-10.
WHO. (2021). Cardiovascular diseases (CVDs). World Health Organization. Web.