Intramuscular Anabolic Signaling and Endocrine Response

The article “Intramuscular anabolic signaling and endocrine response following high volume and high-intensity resistance exercise protocols in trained men” has the purpose of examining mTORCI signaling. mTORCI signaling during the training on two different protocols: HV (high volume) and HI (high intensity). This study has several main findings. First of all, there is practically no margin in mentioned protocols in testosterone response. Secondly, HV, compared to HI, has greater growth hormone, cortisol and insulin. Thirdly, after all, a conclusion is that the two protocols almost similarly stimulate mTORCI activation during resistance exercises.

The study has some strengths and weaknesses in its design. The first strength is that it used a multidimensional analysis, such as biochemical, intramuscular anabolic signaling, statistical, and electromyography. This method allows coming to the most objective results in the end. The second strength is working with a participant in the study; scientists recruited ten resistance-trained men with practically similar physical characteristics. Furthermore, participants had to provide a urine sample, control a diet, duplicate “the content, quantity, and timing of their daily diet” (Gonzales et al., 2015, p. 5), and do other activities. The study’s weakness is the small sample of experiment participants, which can affect the objectivity of results. Another weakness is the small number of exercises; the results might have been different if more of them had been done.

The information from this article is helpful for a sport scientist for several reasons. To begin, the work enlightens the fact that, after all, there is no significant difference between HV and HI resistance exercises when they activate mTORCI. It allows one to look from a new point of view at the problem of muscle growth because mTORCI takes part in this process. A sport scientist can apply the article in compiling the most appropriate, productive, and effective system of physical exercises. Moreover, the absence of significant differences in testosterone response to these two protocols may help study testosterone’s impact and role in the organism. However, the growth hormone, cortisol, and insulin responses are greater in HV protocol; a sport scientist may use this fact to study the nature of these hormones during such physical exercises.

Reference

Gonzalez, A. M., Hoffman, J. R., Townsend, J. R., Jajtner, A. R., Boone, C. H., Beyer, K. S., Baker, K. M., Wells, A. J., Mangine, G. T., Robinson, E. H., 4th, Church, D. D., Oliveira, L. P., Willoughby, D. S., Fukuda, D. H., & Stout, J. R. (2015). Intramuscular anabolic signaling and endocrine response following high volume and high intensity resistance exercise protocols in trained men. Physiological reports, 3(7), e12466.

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StudyCorgi. (2023) 'Intramuscular Anabolic Signaling and Endocrine Response'. 4 March.

1. StudyCorgi. "Intramuscular Anabolic Signaling and Endocrine Response." March 4, 2023. https://studycorgi.com/intramuscular-anabolic-signaling-and-endocrine-response/.


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StudyCorgi. "Intramuscular Anabolic Signaling and Endocrine Response." March 4, 2023. https://studycorgi.com/intramuscular-anabolic-signaling-and-endocrine-response/.

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StudyCorgi. 2023. "Intramuscular Anabolic Signaling and Endocrine Response." March 4, 2023. https://studycorgi.com/intramuscular-anabolic-signaling-and-endocrine-response/.

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