The concept of how biological compounds influence the health status of an individual is intriguing for research. For instance, how assimilated substrates such as glucose and amino acids induce obesity and other metabolic disorders make in-depth knowledge of nutritional biochemistry important. The article’s topic captivates attention since it informs the reader of the journal issue discussing polyphenols, which are mainly obtained from the diet, and health complications acquired through the utilization of foods. Currently, there are research interests in phenols, their mechanisms of action as bioactive compounds, and their implications as potential remedies for metabolically induced diseases such as obesity (Bruno et al., 2021). Having an overview of the papers in the journal issue from this article, I would like to do further studies and practical research on unfulfilled concepts of polyphenol bioactivities.
The article specifically reveals the link between biochemistry and nutrition as essential tools for attaining holistic health. The reader’s attention should focus on understanding concepts in the papers within the journal issue and developing research questions for further empirical and analytical studies. Specifically, the paper discussing the reduction of obesity through the consumption of polyphenol-rich food such as apples would deliver many indications of dietary remedies. Moreover, it is an article that is less than a month old, discussing the medical implications of polyphenols in the Journal of Nutritional Biochemistry (Bruno et al., 2021). Even though it has not been cited in research papers, it recommends the appropriate gaps to bridge through research by compiling previous concepts precisely.
The review paper addressed research concepts on polyphenols that human beings frequently consume in food. Furthermore, it pointed out the biomedical significance of the identified compounds and their mechanisms for mitigating metabolic health disorders. The objective was accomplished through the selection of research papers discussing the nutritional significance of polyphenols. Nearly 24 articles specifically addressing the efficacy of polyphenols in alleviating cardio-metabolic complications and their broad-spectrum activity against diseases of the heart, liver, and alimentary canal were reviewed (Bruno et al., 2021). Compiling information from different authors into one article is an approach that allowed for a resolute conception of ideas.
The author of the article used the systematic review approach in achieving the objective of the research. Empirical data about previous research activities and contextual discussions were executed. The graph on previous research activities indicated that research on polyphenols was low until the 21st century reached with technological advancements. A detailed compilation of previous experimental research concepts was analyzed under topics focusing on the activities of polyphenols on specific metabolic diseases (Bruno et al., 2021). It allowed for a successful determination of how foods with high polyphenol contents can be recommended for therapeutic purposes against heart, liver, and gut diseases. It was realized that polyphenols are effective against inflammation of the gut-liver axis and reduction of hyperglycemia.
Through a comprehensive review of the assembled articles, it is acceptable that polyphenols are effective against obesity and heart diseases stemming from metabolic disorders. However, some studies highlighted that polyphenols have no direct impact on the health complications of interest. Instead, interactive metabolites from the microbial flora exhibited some efficacy with the indirect influence of polyphenols. Further research was recommended to eliminate the controversy existing regarding the direct efficacy of polyphenols in reducing health risks (Bruno et al., 2021). Moreover, the mechanisms of action of the compounds from different foods are worth investigating to determine their similarities and differences in the targeted diseases.
It is essential to research the biochemical significance of polyphenols or mitigating metabolic disorders. Moreover, a thematic discussion of insights pertaining to the compounds’ efficacy as nutritional remedies enhanced the clarity of the paper. Deep in its content, the journal issue connects polyphenols as nutritional products with their mechanisms of action in obesity and heart problems. It motivates the reader to invest time in obtaining the articles for more information. Moreover, it inspires us to question insightfully how polyphenols can be harnessed as nutritional remedies for the diseases of interest.
Reference
Bruno, R. S., Neilson, A. P., Lambert, J. D., & Moustaid-Moussa, N. (2021). Journal of nutritional biochemistry special issue: Polyphenols, obesity, and cardiometabolic health. Journal of Nutritional Biochemistry, 89, 1−3. Web.