Chlamydial Infection: Pathophysiology and Prevention

The pathophysiologic instruments of chlamydial contagion are not implicit comprehensively. Chlamydia contaminates columnar epithelial cells that put the pubescent woman at actual danger due to the occurrence of the squamocolumnar intersection on the ectocervix waiting for the premature maturity. The original reaction of epithelial cells to the contagion is a neutrophilic permeation, trailed by lymphocytes, macrophages, plasma cells, and eosinophilic incursion (Samoff, Koumans, & Markowitz, 2005).

The discharge of cytokines and interferons by the disease-ridden epithelial cell resets the following seditious flow. The virus is typically transmitted during sex. A diseased man possesses an opportunity of twenty-five per cent during the sexual activity of conveying the contagion to a healthy woman. Chlamydiae could also be precipitously transmitted. The infection proportion from a diseased woman to her child is more than fifty per cent, triggering such illnesses as conjunctivitis or pneumonia in most of the instances. Chlamydial infection regularly is instigated by sexual contact of any kind.

C trachomatis contagion disturbs the cervix, urethra, salpinges, uterus, nasopharynx, and epididymis; it appears to be the most frequently conveyed infectious sexually transmitted disease (STD) in America (Stamm, 2008). C trachomatis contagion is the reason for other illnesses too, counting afebrile pneumonia syndrome and trachoma.

C pneumoniae contagion is transmitted by the means of respirational precipitations and is the reason for pharyngitis, bronchitis, and pneumonia. C psittaci contagion is transmitted by fowl feces and sprays and leads to psittacosis.

Moreover, to the situations registered in the discrepancy analysis, additional issues problems could be included, such as Bacterial vaginosis, Fitz-Hugh-Curtis disease, sterility, mycoplasma genitalium contagion, Periurethral swelling, gravidity, Prostatitis, Salpingitis, Tubo-ovarian eruption, and Ureaplasma contagion.

Chlamydia examinations include an example of fluid or urine in order to determine if the chlamydia microorganisms, which is called Chlamydia trachomatis are existing in the organism and triggering a contagion. The examinations that are applied in order to determine the presence of a chlamydia contagion contain nucleic acid amplification tests (which are referred to as NAAT) and Chlamydia bacteria sampling. The effects of the latter need more time (from four to eight days) compared to the acid amplification tests.

Chlamydia infection could be treated with antibiotics without difficulty. HIV-positive people with the infection have the opportunity to obtain the identical handling as the people who are HIV-negative.

The individuals with the chlamydia infection ought to give up the sexual intercourse for at least a week after taking the first dosage of the medicine or after the finishing point of a week-long course of the necessary medicine in order to avert transmitting the chlamydia bacteria to their sexual partners. It is vital to take all of the medicine recommended by the doctor in order to treat the chlamydia infection. The patient that is prescribed with the medicine for chlamydia infection is forbidden to share with another person. Even though the medicine will prevent the contagion from spreading, it will not restore any perpetual harm caused by the sickness. If cases when an individual’s signs of an infection endure for more than several days after getting the medicine, he or she have to go back to a doctor in order to be reexamined.

The most operative and efficient method of preventing the chlamydia infection is to evade sexual connections, especially with the infected individuals. Nonetheless, as this solution appears to be not applied for the majority of the population, there are several other measures in preventing the disease from spreading, such as wearing a condom.

References

Samoff, E., Koumans, E., & Markowitz, L. (2005). Association of Chlamydia trachomatis with persistence of high-risk types of human papillomavirus in a cohort of female adolescents. American Journal of Epidemiology, 162(7), 668-675.

Stamm, W. (2008). Chlamydia trachomatis infections of the adult. New York, NY: McGraw-Hill.

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