The article by the Scripps Research Institute highlights the expected positive effects of a recent chemical discovery – now there is a general method that allows for the synthesis of 1,2,3,5-tetrazines, a previously unknown compound family. About sixty years ago, closely related 1,2,4,5-tetrazines were found, and their success and invaluable impact on pharmacy ensure chemists in the effectiveness of the newly discovered compounds, especially considering their differentiating reactivities (Scripps Research Institute). Advanced chemical products like biological probes and pharmaceuticals have become more likely with the introduction of an efficient and less challenging synthesizing method, as compared with the approach used in 2019 to synthesize the first compound. The initial process only allowed to make one compound and was rather laborious; however, today, there is a path to create numerous variations of these compounds. 1,2,3,5-tetrazine can efficiently react with amidines through ligations, meaning that new biological labeling techniques, molecular probes, and other advances are expected soon.
Work Cited
Scripps Research Institute. “Chemists Develop Reactions for the General Synthesis of Promising Unexplored Compounds.” ScienceDaily, Web.