Gram-Positive vs. Gram-Negative Cell Walls

It’s worth noting that the majority of bacteria own a cell layer, which normally contains one of two varieties, such as gram-positive or gram-negative. The cell layer of gram-positive microorganisms is made up of numerous coatings of peptidoglycan, which creates a hard and robust layer. Teichoic acids and phosphate are also found in its cellular membrane (Parker et al., 2016). The lipoteichoic acid and the teichoic layer acid form two teichoic acid components found in gram-positive microorganisms. Murein is indeed the main protein that makes up the cell layer.

In contrast, the structural layer of gram-negative bacteria consists of an internal cell compartment and numerous sections of peptidoglycan. Lipoproteins, phospholipids, and lipopolysaccharide comprise the surface protective layer of the cell. Lipoproteins of the surface layer of the cell, which are found in the fluid-like periplasm in the middle of the cell membrane and the surface layer of the cell, retain the peptidoglycan (Parker et al., 2016). Proteins and degradation enzymes are found in the periplasm, and they aid in the movement of molecules. Someone needs to know a gram stain because it aids the practitioners in determining whether an individual has a bacterial illness and the kind of bacteria is inflicting the disease. It can assist the specialist come up with a good treatment strategy.

The phylum Chlamydiae is a type of bacteria that seems to be absent peptidoglycan, even though their outer layers are gram-negative in every other way. The bacteria make use of a protein surface that works similarly to peptidoglycan. However, the cell usually benefits since it is protected from beta-lactam antibiotics which usually destroy peptidoglycan. Bacteria found in the group of the phylum Tenericutes have no cell walls, making them particularly sensitive to osmotic fluctuations (Parker et al., 2016). Sterols, a chemical commonly found in eukaryotic cell walls, are frequently added to reinforce their cell walls. Most species of the phylum are microorganisms that prefer to lurk in the safe confines of a carrier.

Reference

Parker, N., Schneegurt, M., Thi Tu, A. H., Foster, B. M., & Lister, P. (2016). Microbiology (OpenStax).

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