Healthcare Research: Systematic Search Strategy

Introduction

To find relevant literature on the PICOT topic, MEDLINE, PubMed, and Embase databases were used. MEDLINE is a database maintained by the National Library of Medicine (NLM) that contains references to journal articles, mostly in the field of biomedicine. PubMed is a subset of MEDLINE, although it includes more book and chapter references and has a broader subject focus. Embase is a biological bibliographic database that comprises journal papers published since 1947 and gives information based on regulatory medication selection standards. To boost the sensitivity of the search, the search phrases contained keywords related to the PICOT query while conducting exhaustive database searches. The keywords were “standardized use of BIS during anesthesia,” “BIS monitoring,” and “BIS monitoring in prevention of unintended awareness.” For updating previously published systematic reviews, date limitations were set on the database when looking for relevant material.

Discussion

The inclusion criteria for the databases were the exposure of interest, reported outcomes, and publication type. First, as the PICOT question investigates medical issues, the authors need to have the medical knowledge to be considered for inclusion. Second, the inclusion of the study may depend on whether specific outcomes of relevance have been reported promptly and consistently. Third, the original studies were mainly sought as a piece of research evidence in this systematic review. The geographic location of the study was taken as an exclusion criterion, as the PICOT question examines the general topic and does not limit the geographic location.

Overall, 10 published articles and reviews were found to address the PICOT question. Gao et al. (2018) examined the use of bispectral index monitoring (BIS) in an intraoperative setting in their published meta-analysis article. Gruber et al. (2022), Lee et al. (2019), Shetty et al. (2018) qualitative studies and Tasbihgou et al.’s (2017) narrative review also use their published observational results for the research. In their research articles, Lewis et al. (2019) and Akavipat et al. (2021) used the quantitative research method as the research evidence for their studies. In their review article, Oliveira et al. (2017) studied the benefits of using BIS monitoring in a perioperative setting based on a meta-analysis and systematic review.

Conclusion

The paper investigated the efficiency of BIS monitoring in their published systematic meta-analysis and used quantitative and observational results to examine the issue. Meantime, a published qualitative study conducted by Li et al. (2018) studied the evaluation of using BIS monitoring compared to standard monitoring practices in an intraoperative setting.

References

Akavipat, P., Eiamcharoenwit, J., Punjasawadwong, Y., Pitimana-aree, S., Sriraj, W., Laosuwan, P., Viengteerawat, S., & Wasinwong, W. (2021). Unintended intraoperative awareness: An analysis of preoperative anesthetic adverse events in Thailand. International Journal of Risk & Safety in Medicine, 32(2), 123-132. Web.

Bocskai, T., Kovács, M., Szakács, Z., Gede, N., Hegyi, P., Varga, G., Pap, I., Tóth, I., Révész, P., Szanyi, I., Németh, A., Gerlinger, I., Karádi, K., & Lujber, L. (2020). Is the bispectral index monitoring protective against postoperative cognitive decline? A systematic review with meta-analysis. PLOS One, 15(2): e0229018 Web.

Gao, W., He, Y., Liu, L., Yuan, Q., Wang, Y., & Zhao, B. (2018). BIS monitoring on intraoperative awareness: A meta-analysis. Current Medical Science, 38(2), 349-353. Web.

Gruber, B. U., Girsberger, V., Kusstatscher, L., Funk, S., Luethy, A., Jakus, L., Maillard, J., Steiner, L. A., Dell-Kuster, S., & Burkhart, C. S. (2022). Comparing propofol anaesthesia guided by Bispectral Index monitoring and frontal EEG wave analysis with standard monitoring in laparoscopic surgery: protocol for the ‘EEG in General Anaesthesia – More Than Only a Bispectral Index’ Trial, a multicentre, double-blind, randomised controlled trial. BMJ Open, 12, e05991. Web.

Lee, C.C., Wang, TL., Ironstone, S. (2020). Unintended Wake-Up During Neurosurgery. In: Brambrink, A., Kirsch, J. (eds) Essentials of Neurosurgical Anesthesia & Critical Care. Springer, Cham. Web.

Lewis, S. R., Pritchard, M. W., Fawcett, L. J., & Punjasawadwong, Y. (2019). Bispectral index for improving intraoperative awareness and early postoperative recovery in adults. Cochrane Database of Systematic Reviews. Web.

Li, Z., Cai, J., Li, J., Xu, X., & Zheng, L. (2021). Comparative evaluation of the bispectral index (BIS) and BISpro during propofol anaesthesia. Journal of International Medical Research, 49(4). Web.

Oliveira, C. R. D., Bernardo, W. M., & Nunes, V. M. (2017). Benefit of general anesthesia monitored by bispectral index compared with monitoring guided only by clinical parameters. Systematic review and meta-analysis. Brazilian Journal of Anaesthesiology, 67(1), 72-84. Web.

Shetty, R. M., Bellini, A., Wijayatilake, D. S., Hamilton, M. A., Jain, R., Karanth, S., & Namachivayam, A. (2018). BIS monitoring versus clinical assessment for sedation in mechanically ventilated adults in the intensive care unit and its impact on clinical outcomes and resource utilization. Cohrane Library, 21(2). Web.

Tasbihgou, S. R., Vogles, M. F., & Absalom, A. R. (2017). Accidental awareness during general anaesthesia – a narrative review. Anaesthesia, 73(1), 112-122. Web.

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